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After studying Medicine and Biophysics at the University of Leipzig he started his career as a surgeon at the St.Georg-Hospital Leipzig. Based on a research grant he started in 1989 a research project on precursor examination during protein synthesis at Cornell University in New York. After his return to Germany, he started to introduce laparoscopic bariatric surgery in Frankfurt at the Northwest Hospital. He became a professor of surgery at the Goethe University of Frankfurt. He was head and director of the Hospital Sachsenhausen in Frankfurt from 2001-2014. Until 2006 more than 50 % of bariatric surgeries were performed in this first COE in Germany. In October 2014 the first and largest clinic for Metabolic surgery (42 beds) in Sana Hospital Offenbach was founded. Since 1998 he has been organizing the Frankfurt meeting as the largest live-surgery meeting for bariatric surgery.
Prof. Weiner founder and president of the German Society for Surgery of Obesity and Metabolic Disorders, president of the European Chapter of IFSO, president of the IFSO World Congress 2011 in Hamburg with the first invitation of IBC-Club, president of IFSO 2014-2015.
He received many awards and prizes (Virchow, Thiersch, Sauerbruch, Pichlmayr and others), the IFSO poster prizes in 2006 and 2013 and became an Honorary member of ASMBS in 2016 and other national societies.
He performed during the 4 decades more than 12.000 bariatric procedures and published more than 400 scientific papers, 10 books and more than 20 book chapters.
Prof. Weiner is Associate Editor of Obesity Surgery and Member of the Editorial Board of SOARD and 8 other scientific journals.