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The management of anal fistulas is one of the greatest challenges. The need to preserve continence while permanently eradicating the fistula is the ultimate desired goal. Unfortunately, none of the ever-expanding myriads of treatments is a panacea; high rates of failure and of recurrence are consistently experienced. Regenerative or autologous tissue replacement therapies differ from all other options in encouraging tissue growth rather than destroying, ablating, or excising tissue. This program will demonstrate the role of autologous stem cells and gracilis muscle interposition in the treatment of some of the most challenging fistulas.
  1. Welcome & Introduction – Dr. Steven D. Wexner (USA) 

  2. How Regenerative Medicine is Changing the Treatment of Inflammatory Bowel Disease - Dr. Amy Lightner (USA)

  3. The results of stem cells for fecal incontinence - Dr. Lucia Oliveira (Brazil)

  4. Development of stem cells for fistulas - Dr. Damian Garcia (Spain)

  5. Treating incontinence after fistula surgery – Dr. Liliana Bordeianou (USA)

  6. The results of gracilis interposition for complex perineal fistulas - Dr. Sameh Emile (Egypt)

  7. Video gracilis interposition for rectovaginal and rectourethral fistulas - Dr. Zoe Garoufalia (Greece)

  8. Panel discussion & Closing Remarks  - All faculty moderated by Dr. Steven D. Wexner (USA)

*Supported by an educational grant from Takeda Pharmaceuticals U.S.A.


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Dr. Liliana Bordeianou MD, Professor of Surgery, Harvard Medical School; ;Director, Massachusetts General Hospital Colorectal Surgery and Pelvic Floor Disorders Centers; Co-Chair, Mass General Brigham Healthcare Network Colorectal Surgery Collaborative, Boston, USA Colorectal Surgery
Dr. Damian Garcia Olmo MD, PhD, Professor Of Surgery, Universidad Autónoma De Madrid; Chief, Department of Surgery, Fundación Jiménez Díaz University Hospital, Spain General Surgery
Dr. Zoe Garoufalia Clinical Fellow, Minimally Invasive Colorectal Surgery, Cleveland Clinic Florida; Chair, Y- ESCP; Chair of Communications Committee, ASCRS, USA Colorectal Surgery
AIS Ambassador
Dr. Amy Lightner MD, Professor of Surgery, Scripps Clinic; Chief Medical Officer, Direct Biologics LLC, USA General Surgery
Dr. Lucia Oliveira MD, PhD, FASCRS, Consultant Colorectal Surgeon, Hospital Casa de Saude São José and Director Anorectal Physiology Dept.of Rio de Janeiro, Brazil Colorectal Surgery
Dr. Steven D. Wexner MD, PhD, Editor-in-Chief, Surgery, Past Vice Chair, Board of Regents, American College of Surgeons, Director, Ellen Leifer Shulman and Steven Shulman Digestive Disease Center and Chair, Department of Colorectal Surgery, Cleveland Clinic Florida, USA Colorectal Surgery
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