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The COLOR trials (COlon carcinoma Laparoscopic or Open Resection) are large, randomized and prospective studies that involve multiple centers in Europe. They are designed to obtain the strongest level of evidence regarding to minimal invasive surgery and colorectal cancer.

The first one started 17 years ago and compared laparoscopy vs open surgery for colorectal cancer, then came the COLOR II dedicated to rectal cancer and the third is being designed to address taTME vs laparoscopic TME.

In the video Jaap Bonjer will review historical details, design, results and the impact of these trials.

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