Universal Tumor Screening for Lynch Syndrome - past, present and future

Lynch Syndrome is an hereditary condition that entails a higher risk of colorectal cancer, endometrial cancer and other cancers. The main genetic feature is the presence of mutations in MMR genes leading to microsatellite instability (MSI). In this lecture, Dr. Heather Hampel guides us through the history of LS diagnosis, from the past, to the future expectations, with a review of the current practices, a must-know for all colorectal surgeons.