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The 2nd AIS SurgEndocrine Event was devoted to parathyroid gland handling during a total thyroidectomy. Two live total thyroidectomies were performed with a specific focus on parathyroid gland preservation. Faculty and viewers across the world interacted with the surgeons during the procedure, and a debriefing session between chairs and faculty took place at the end of the meeting. Parathyroid gland management issues regarding to postoperative hypocalcemia and hypoparathyroidism were discussed.