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Single-anastomosis Duodeno-ileal Bypass with Sleeve Gastrectomy (SADI-S) is an increasingly common and effective operation for treatment of obesity and weight-related co-morbidities. In addition to the technical conduct of the operation, patient selection and education for the procedure are critical to attain optimal outcomes. This lecture covers the latest data on outcomes including weight loss, improvement of metabolic disease, and complications. Operative details of the procedure, including tips and tricks as well as variations are discussed. Additional focus is placed on identifying the correct patients who will most benefit from this metabolic procedure, including indications, contra-indications, and follow-up paradigms.
